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PRESENT STUDENTS:
Major Advisor for:
Justin Crawford, Physics
James Germann, Physics
Jason King, Physics
You Li, Physics
William Robinson, Physics Committee
Member for:
Subhashini
Chitta, Mechanical Aerospace, and Biomedical Engineering
Howard Frederick, Physics
Jesse
Ogle, Physics
Depak
Raijput, Materials Science
Joshua Whitney, Physics
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STUDENT THESES
AND DISSERTATIONS |
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SELECTED
PUBLICATIONS:
Triplet-state
investigations of fluorescent dyes at dielectric interfaces using
total internal reflection fluorescence correlation spectroscopy,
H. Blom, A. Chmyrov, K. Hassler, L.M. Davis,| and J.
Widengren, J. Phys. Chem A, 113, 5554-5566
(2009).
Single-pulse
ultrafast-laser machining of high aspect nano-holes at the surface
of SiO2, Y.V. White, X. Li, Z. Sikorski, L.M. Davis,
and W. Hofmeister, Optics Express 16, 14411-14420 (2008).
Electrokinetic
delivery of single fluorescent biomolecules in fluidic nanochannels,
L.M. Davis, B.K. Canfield, X. Li, W.H. Hofmeister, I.P. Lescano-Mendoza,
B.W. Bomar, J.P. Wikswo, D.A. Markov, P.C. Samson, C. Daniel, Z.
Sikorski, and W. Robinson, in Biosensing, ed. by M. Razeghi
and H. Mohseni, Proceedings of SPIE 7035, 70350A, 1-12
(2008).
Femtosecond
micro- and nano-machining of materials for microfluidic applications,
Y.V. White, M. Parrish, X. Li, L.M. Davis, W. Hofmeister, in
Nanoengineering: Fabrication, Properties, Optics, and Devices V,
ed. by E.A. Dobisz and L.A. Eldada, Proceedings of SPIE 7039,
70390J, 1-10 (2008).
Engineering
the collected field for single-molecule orientation determination,
Z. Sikorski and L.M. Davis, Optics Express 16, 3660-3673
(2008).
Maximum-likelihood
position sensing and actively controlled electrokinetic transport
for single-molecule trapping, L. Davis, Z. Sikorski, W.
Robinson, G. Shen, X. Li, B. Canfield, I. Lescano, B. Bomar, W.
Hofmeister, J. Germann, J. King, Y. White, and A. Terekhov, in
Single-molecule spectroscopy and imaging, ed. by J. Enderlein,
Z.K. Gryczynski, R. Erdmann, Proceedings of SPIE 6862,
68620P, 1-10 (2008).
Fabrication
and characterization of nanofluidics device using fused silica for
single protein molecule detection, X. Li, W. Hofmeister, G.
Shen, L.M. Davis, and C. Daniel, in Medical Device Materials IV
(Proceedings of Materials and Processes for Medical Devices 2007) ,
ed. by J. Gilbert, ASM International, 2008, pp. 145-150 (2008).
Engineering
of illumination and collection field profiles for single-molecule
orientational imaging, Z. Sikorski and L.M. Davis, in
Complex Light and Optical Forces, ed. by D.L. Andrews, E.J.
Galvez, G. Nienhuis, Proceedings of SPIE 6483, 64830K, 1-12
(2007).
Extension
of multidimensional microscopy to ultrasensitive applications with
maximum-likelihood analysis, Lloyd M. Davis and Guoqing Shen,
in Three-Dimensional and Multidimensional Microscopy: Image
Acquisition and Processing XIV, ed. by J.-A. Conchello, C.J.
Cogswell, T. Wilson, Proceedings of SPIE 6443, 64430N,
1-12 (2007).
Single-molecule
detection with axial flow into a micrometer-sized capillary,
D.A. Ball, G. Shen, and L.M. Davis, Applied Optics 46,
1157-1164 (2007).
Accounting
for triplet and saturation effects in fluorescence correlation
spectroscopy measurements, L.M. Davis and G.Q. Shen, Current
Pharmaceutical Biotechnology 7, 287-301 (2006).
Saturation
effects in fluorescence correlation spectroscopy," L.M. Davis,
G.Q. Shen, and D.A. Ball, paper 5700-25, in Multiphoton
Microscopy in the Biomedical Sciences, ed. by A. Periasamy,
P.T.C. So, Proceedings of SPIE 5700, 128-137 (2005).
Data
reduction methods for application of fluorescence correlation
spectroscopy to pharmaceutical drug discovery, L.M. Davis, P.E.
Williams, D.A. Ball, E.D. Matayoshi, and K.M. Swift, Current
Pharmaceutical Biotechnology
4, 451-462 (2003);
5, 481-481 (2004)
Dealing
with reduced data acquisition times in fluorescence correlation
spectroscopy for HTS applications, L.M. Davis, D.A. Ball, P.E.
Williams, E.D. Matayoshi, and K.M. Swift, in Microarrays and
Combinatorial Technologies for Biomedical Applications, ed. by
D.V. Nicolau and R. Raghavachari, Proceedings of SPIE 4966,
117-128 (2003).
Multiplexed
analysis using time-resolved near-IR fluorescence for the detection
of genomic material, W.J. Stryjewski, S.A. Soper, S. Lassiter,
and L.M. Davis, in Biomedical Nanotechnology Architectures and
Applications, ed. by D.J. Bornhop, D.A. Dunn, R.P. Mariella,
Jr., C.J. Murphy, D.V. Nicolau, Sr., S. Nie, M. Palmer, R.
Raghavachari, Proceedings of SPIE 4626, 201-209 (2002).
Imaging
of single-chromophore molecules in aqueous solution near a
fused-silica interface, L.M. Davis, W.C. Parker, D.A. Ball,
J.G.K. Williams, G.R. Bashford, P. Sheaff, R. Eckles, D.T. Lamb, and
L.R. Middendorf, in Multiphoton Microscopy in the Biomedical
Sciences, ed. by A. Periasamy, P.T.C. So, Proceedings of SPIE
4262, 301-311 (2001).
Analysis
of ultrasensitive fluorescence experiments, L.M. Davis,
Y. Sun, and B. Whitehead, in Advances in Fluorescence Sensing
Technology IV, ed. by J.R. Lakowicz, S.A. Soper, R.B.
Thompson, Proceedings of SPIE 3602, 379-390 (1999).
Computer
simulation of gene detection without PCR by single molecule
detection, L.M. Davis, J.G.K. Williams, and D.T. Lamb, in
Biomedical Sensors, Fibers, and Optical Delivery Systems, ed. by
F. Baldini, N.I. Croitoru, M. Frenz, I. Lundstrom, M. Miyagi, R.
Pratesi, O.S. Wolfbeis, Proceedings of SPIE 3570, 282-293
(1999).
Avalanche
detector with ultra-clean response for time-resolved photon counting,
A. Spinelli, M. Ghioni, S. Cova, and L.M. Davis, IEEE Journal of
Quantum Electronics, 34, 817-821 (1998).
Monte
Carlo simulation of a single molecule detection experiment, D.H.
Bunfield and L.M. Davis, Applied Optics 37, 2315-2326 (1998).
Single
molecule detection for ultrasensitive analysis and separations on
microchips, J.C. Fister III, S.C. Jacobson, L.M. Davis, and J.M.
Ramsey, Analytical Chemistry 70, 431-437 (1998).
Actively
quenched single photon avalanche diode for high repetition rate
time-gated photon counting, A. Spinelli, L.M. Davis, and H.
Dautet, Review of Scientific Instruments 67, 55-61 (1996).
Rapid
and efficient detection of single chromophore molecules in aqueous
solution, L.Q. Li and L.M. Davis, Applied Optics 34,
3208-3217 (1995).
Ultrasensitive sub-nanosecond time-gated detection using a single
photon avalanche diode, L.M. Davis and L.Q. Li, in Applications
of Photonic Technology, ed. by G.A. Lamppropoulos, J.
Chrostowski, and R.M. Measures, pp. 483-488, Plenum, New York and
London (1995).
The photophysical constants of several fluorescent dyes pertaining
to ultrasensitive fluorescence spectroscopy, S.A. Soper, E.B. Shera,
L.M. Davis, H.L. Nutter, and R.A. Keller, Photochemistry and
Photobiology 57, 972-977 (1993).
Single
photon avalanche-diode for single-molecule detection, L.Q. Li
and L.M. Davis, Review of Scientific Instruments 64,
1524-1529 (1993).
Picosecond
resolved evolution of laser breakdown in gases, L.M. Davis, L.Q.
Li, and D.R. Keefer, Journal of Physics D: Applied Physics 26,
222-230 (1993).
Detection
and identification of single molecules in solution, S.A. Soper,
L.M. Davis, and E.B. Shera, Journal of the Optical Society of
America B: Optical Physics 9, 1761-1769 (1992).
Use
of streak camera for time resolved photon counting fluorimetry,
L.M. Davis and C. Parigger, Measurement Science & Technology 3,
85-90 (1992)
Rapid
sequencing of DNA based on single molecule detection, S.A.
Soper, L.M. Davis, F.R. Fairfield, M.L. Hammond, C.A. Harger, J.H.
Jett, R.A. Keller, B.A. Marrone, J.C. Martin, H.L. Nutter, E.B.
Shera, and D.J. Simpson, in Optical Methods for Ultrasensitive
Detection and Analysis: Techniques and Applications, ed. by B.L.
Fearey, Proceedings of SPIE 1435, 168-178 (1991).
Rapid
DNA sequencing based upon single molecule detection, L.M.
Davis, F.R. Fairfield, J.H. Hahn, C.A. Harger, J.H. Jett, R.A.
Keller, L.A. Krakowski, B.A. Marrone, J.C. Martin, H.L. Nutter, R.L.
Ratliff, E.B. Shera, D.J. Simpson, and S.A. Soper, Genetic Analysis
Biomolecular Engineering 8, 1-7 (1991).
Laser treatment, J.R. Forwood and L.M. Davis, U.S. Patent
07/551,100 Granted by with U.S. Dept of Commerce (1991).
Detection
of single fluorescent molecules, E.B. Shera, N.K. Seitzinger,
L.M. Davis, R.A. Keller, and S.A. Soper, Chemical Physics Letters
174 (6), 553-557 (1990).
Einstein-Podolsky-Rosen
and Bell's inequality experiments using time and frequency, L.M.
Davis, Physics Letters A 140, 275-279 (1989).
Atomic response to bichromatic crossed beam fields, W.M. Ruyten,
L.M. Davis, C. Parigger, and D.R. Keefer, in Advances in Laser
Sciences-III, ed. by A.C. Tam, J.O. Gole, W.C. Stwalley.
American Institute of Physics Proceedings 172, 155-157
(1988). |
